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Case report: cytomegalovirus primoinfection may be associated with severe outcome in burns

C Augris1, M Benyamina, F Rozenberg

  • 1Burns Centre, Cochin Hospital, University Paris 5, Paris, France.

Annals of Burns and Fire Disasters
|October 13, 2011
PubMed

Insights

Severe cytomegalovirus (CMV) infection can be fatal in burn patients. Monitoring and prevention strategies, including using skin allografts and blood products for seronegative patients, are crucial for managing this risk.

Area of Science:

  • Infectious Diseases
  • Burn Medicine
  • Virology

Background:

  • Burn patients exhibit immunodeficiency, increasing susceptibility to opportunistic infections.
  • Cytomegalovirus (CMV) is a potential pathogen in immunocompromised individuals.
  • Unexplained fever in burn patients warrants investigation into viral etiologies like CMV.

Observation:

  • Two cases of severe primary CMV infection were observed in critically burned patients.
  • CMV infection was suspected as a contributing factor to the fatal outcomes in both cases.

Findings:

  • Cytomegalovirus primoinfection poses a significant threat to severely burned patients.
  • The viral infection may have played a role in the mortality of the reported cases.

Implications:

  • Implementing CMV monitoring and prevention strategies is vital for high-risk burn patients.
  • Prophylactic measures such as using CMV-screened skin allografts and blood products for seronegative patients are recommended.
  • Early recognition and management of CMV are essential to improve outcomes in burn care.
Keywords:
ASSOCIATEDBURNSCASECYTOMEGALOVIRUSOUTCOMEPRIMOINFECTIONREPORTSEVERE

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