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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
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Related Experiment Video

Updated: May 28, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Real-time high-speed volumetric imaging using compressive sampling optical coherence tomography.

Mei Young, Evgeniy Lebed, Yifan Jian

    Biomedical Optics Express
    |October 13, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Compressive Sampling (CS) reduces Optical Coherence Tomography (OCT) acquisition time for Optic Nerve Head (ONH) imaging. This technique enhances visualization of deep ONH structures, validating CS-OCT for faster, high-resolution volumetric imaging.

    Keywords:
    (100.0100) Image processing(110.4500) Optical Coherence Tomography

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    Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging

    Published on: November 19, 2012

    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Biomedical Engineering

    Background:

    • Volumetric imaging of the Optic Nerve Head (ONH) using Optical Coherence Tomography (OCT) demands dense sampling, leading to prolonged acquisition times.
    • Compressive Sampling (CS) offers a potential solution by enabling sparse data acquisition and software-based reconstruction to minimize imaging duration and data loss.

    Purpose of the Study:

    • To demonstrate the efficacy of real-time Compressive Sampling Optical Coherence Tomography (CS-OCT) for volumetric imaging of the Optic Nerve Head (ONH).
    • To evaluate the impact of CS-OCT on acquisition speed and image quality for ONH morphometry.
    • To assess the utility of CS-recovered volumes for visualizing deep ocular structures.

    Main Methods:

    • Utilized a 1060nm Swept-Source OCT prototype system.
    • Implemented real-time Compressive Sampling (CS) for sparse volumetric data acquisition of the ONH.
    • Applied registration and averaging techniques to reconstructed CS-OCT volumes.

    Main Results:

    • Successfully demonstrated real-time CS-OCT for volumetric ONH imaging.
    • CS-recovered volumes, after registration and averaging, showed enhanced visualization of deep scleral and lamina cribrosa structures.
    • The study validated CS-OCT's ability to reduce acquisition time while preserving high resolution in averaged images.

    Conclusions:

    • Compressive Sampling Optical Coherence Tomography (CS-OCT) is a viable method for significantly reducing volumetric imaging time of the Optic Nerve Head (ONH).
    • CS-OCT facilitates enhanced visualization of deep ONH structures, including the sclera and lamina cribrosa, through volume averaging.
    • CS technology can be integrated into existing and new OCT systems with only software modifications, requiring no optical changes.