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Neonatal brucellosis and breast milk.
Abdullah Ceylan1, Murat Köstü, Oğuz Tuncer
1Department of Neonatology, Yüzüncü Yıl University Faculty of Medicine, Van, Turkey.
Indian Journal of Pediatrics
|October 14, 2011
Summary
Neonatal brucellosis in an extremely low birth weight infant was successfully treated. This case suggests Brucella may contribute to prematurity and bronchopulmonary dysplasia.
Area of Science:
- Neonatal Medicine
- Infectious Diseases
- Pediatric Pulmonology
Background:
- Brucellosis is a zoonotic infection with potential transplacental transmission.
- Neonatal brucellosis is rare, especially in extremely low birth weight infants.
- Bronchopulmonary dysplasia (BPD) is a common complication in premature infants.
Observation:
- An extremely low birth weight infant born to a mother treated for brucellosis developed respiratory distress syndrome and subsequently BPD.
- Both mother and infant were diagnosed with brucellosis concurrently at two weeks postpartum.
- The infant presented with symptoms of both neonatal brucellosis and BPD.
Findings:
- Successful treatment of brucellosis and BPD was achieved with appropriate antimicrobial therapy and supportive care.
- Resolution of both neonatal brucellosis and BPD symptoms was observed post-treatment.
- Literature review suggests a potential role of Brucella infection in the development of prematurity and BPD.
Implications:
- This case highlights the importance of considering brucellosis in premature infants presenting with respiratory complications.
- Brucella infection may be an underrecognized factor contributing to adverse pregnancy outcomes, including prematurity and BPD.
- The increasing fetotoxicity of Brucella warrants further investigation into bacterial virulence and host defense mechanisms.
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