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Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells
13:07

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells

Published on: January 30, 2019

Reverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription

Kylie Warren1, David Warrilow, Luke Meredith

  • 1Division of Infectious Diseases, Queensland Institute of Medical Research, Brisbane, QLD, Australia; E-Mails: kylieW@qimr.edu.au (K.W.); davidW@qimr.edu.au (D.W.); lukeMe@qimr.edu.au (L.M.).

Viruses
|October 14, 2011
PubMed
Summary

Host factors are essential for HIV-1 proviral DNA synthesis during reverse transcription. This review details cellular proteins interacting with reverse transcriptase (RT) and influencing this critical viral process.

Keywords:
AKAP149APOBEC3GDHX9DNA topoisomerase IGemin2HDAC1HIV-1HuRINI1SAPSAP18SMNSin3alysl-tRNA synthetasereverse transcriptase

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