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Updated: Jan 12, 2026
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
The complexity of antibody-dependent enhancement of dengue virus infection
Maria G Guzman1, Susana Vazquez
1Department of Virology, PAHO/WHO Collaborating Center for the Study of Dengue and its Vector, "Pedro Kouri" Tropical Medicine Institute of Havana, Cuba;
Abstract:
Antibody-dependent enhancement (ADE) has been proposed as a mechanism to explain dengue hemorrhagic fever (DHF) in the course of a secondary dengue infection. Very recently, Dejnirattisai et al., 2010 [1], published an important article supporting the involvement of anti-prM antibodies in the ADE phenomenon. The complexity of ADE in the context of a secondary dengue infection is discussed here.
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