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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Filoviral immune evasion mechanisms

Parameshwaran Ramanan1, Reed S Shabman, Craig S Brown

  • 1Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.

Viruses
|October 14, 2011
PubMed
Summary

Filoviruses like Ebola and Marburg viruses evade the immune system using viral proteins that block critical antiviral responses. These immune evasion strategies are key to filovirus replication and causing severe disease.

Keywords:
EbolavirusIFN antagonistMarburgvirusinnate immune evasion

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