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Published on: August 21, 2020
Successful kidney transplantation in a patient with multiple endocrine neoplasia type 2A syndrome: case study
S Rudzki1, M Matuszek, J Bicki
1First Department of General, Transplant Surgery, and Clinical Nutrition of the Medical University of Lublin, Poland. klinika-chirurgii@wp.pl
Abstract:
We present the case of a 37-year-old patient diagnosed with multiple endocrine neoplasia type 2A (MEN 2A) syndrome, as confirmed by genetic tests, who underwent the transplantation of a kidney from a cadaveric donor. MEN 2A, a hereditary autosomal dominant syndrome, is caused by the mutation of the RET proto-oncogene. In almost all patients this syndrome, is characterized by the occurrence of medullary thyroid cancer and pheochromocytoma; in some individuals also hyperparathyroidism. The available literature has not documented a kidney transplantation performed in Poland for this indication.
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