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Related Experiment Video

Updated: May 28, 2026

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Robotically assisted fluorescence-guided lymph node mapping with ICG for gynecologic malignancies: a feasibility

Emma C Rossi1, Anastasia Ivanova, John F Boggess

  • 1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, USA. ecrossi@iupui.edu

Gynecologic Oncology
|October 15, 2011
PubMed
Summary
This summary is machine-generated.

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A 1mg dose of Indocyanine green (ICG) successfully identified sentinel lymph nodes (SLNs) in 88% of patients with early-stage cervical and endometrial cancer. Robotically assisted near-infrared imaging proved a safe and effective method for lymphatic mapping.

Area of Science:

  • Gynecologic Oncology
  • Surgical Innovation
  • Medical Imaging

Background:

  • Sentinel lymph node (SLN) mapping is crucial for staging endometrial and cervical cancers.
  • Traditional SLN mapping techniques face challenges in accuracy and efficiency.
  • Near-infrared (NIR) imaging with Indocyanine green (ICG) offers a promising alternative.

Purpose of the Study:

  • To assess the feasibility and determine the optimal dose of ICG for SLN identification.
  • To evaluate robotically assisted endoscopic NIR imaging for pelvic and para-aortic SLN mapping.
  • To establish the efficacy of a 1mg ICG cervical injection dose.

Main Methods:

  • Prospective enrollment of 20 subjects with cervical or endometrial carcinoma.
  • Cervical stroma injection of ICG at 3 and 9 o'clock positions.

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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Related Experiment Videos

Last Updated: May 28, 2026

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

  • Robotically assisted endoscopic NIR imaging for SLN detection and analysis.

    • Main Results:

    • A 1mg ICG dose achieved an 88% SLN detection rate (95% CI: 64%-99%).
    • A median of 4.5 SLNs were identified per patient.
    • No adverse events were reported, indicating a safe procedure.

    Conclusions:

    • A 1mg cervical injection of ICG is effective for SLN identification in 88% of patients.
    • Robotically assisted fluorescence imaging is a feasible, safe, and efficient method for lymphatic mapping.
    • This technique is reliable for early-stage cervical and endometrial cancer staging.