Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization of computer-generated holograms with diffraction-engineered initialization.

Optics express·2026
Same author

Free-Space Skyrmions Radiated from a Geometric Phase Aperture.

ACS nano·2026
Same author

High-fidelity super-resolution microscopy datasets spanning multispectral to hyperspectral domains via diffractive optics.

Scientific data·2026
Same author

pH-Triggered and Targeted Delivery of Curcumin: From Dendritic Polymers to Natural and Synthetic Nanocarriers.

Advanced healthcare materials·2025
Same author

Close-to-atom scale precision measurement and manufacturing via near-field optics.

Science bulletin·2025
Same author

Photophysical behavior of sulfur-oxidized sulfone and trifluoromethyl-BODIPY: Insight into the relationship between crystal structure and tumor cell imaging.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2025

Related Experiment Video

Updated: May 28, 2026

Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

Non-spectroscopic refractometric nanosensor based on a tilted slit-groove plasmonic interferometer.

Xiaowei Li1, Qiaofeng Tan, Benfeng Bai

  • 1State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments, Tsinghua University, Beijing 100084, China. li-xw06@mails.tsinghua.edu.cn

Optics Express
|October 15, 2011
PubMed
Summary

We developed a simple, non-spectroscopic plasmonic interferometer for refractometric sensing. This chip-based sensor uses light interference to detect refractive index changes, offering high sensitivity for various applications.

More Related Videos

Performing Spectroscopy on Plasmonic Nanoparticles with Transmission-Based Nomarski-Type Differential Interference Contrast Microscopy
08:54

Performing Spectroscopy on Plasmonic Nanoparticles with Transmission-Based Nomarski-Type Differential Interference Contrast Microscopy

Published on: June 5, 2019

Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers
09:33

Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers

Published on: March 21, 2025

Related Experiment Videos

Last Updated: May 28, 2026

Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

Performing Spectroscopy on Plasmonic Nanoparticles with Transmission-Based Nomarski-Type Differential Interference Contrast Microscopy
08:54

Performing Spectroscopy on Plasmonic Nanoparticles with Transmission-Based Nomarski-Type Differential Interference Contrast Microscopy

Published on: June 5, 2019

Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers
09:33

Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers

Published on: March 21, 2025

Area of Science:

  • Nanotechnology
  • Optics
  • Sensor Technology

Background:

  • Plasmonic nanosensors are typically based on spectroscopic monitoring of surface plasmon resonance for refractometric detection.
  • Existing methods often require complex spectroscopic equipment, limiting portability and throughput.

Purpose of the Study:

  • To propose and demonstrate a simple, non-spectroscopic refractometric sensing scheme.
  • To develop a chip-based sensor utilizing plasmonic interference for refractive index sensing.

Main Methods:

  • Integration of a metallic groove array and a tilted nanoslit to form a plasmonic interferometer.
  • Utilizing interference between directly transmitted light and surface plasmon polariton-mediated light.
  • Monitoring the spatial shift of high-contrast intensity fringes under monochromatic illumination.

Main Results:

  • Achieved high-contrast intensity fringe detection due to plasmonic interference.
  • Demonstrated a sensitivity of up to 5 × 10³ μm/RIU.
  • Obtained a figure of merit as high as 250.

Conclusions:

  • The proposed non-spectroscopic plasmonic interferometer offers a robust and simple sensing scheme.
  • This technology holds potential for low-cost, portable, and high-throughput refractometric sensing applications.