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Updated: May 28, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
[Cardiac resynchronization therapy for patients with atrial fibrillation]
Attila Mihálcz1, Pál Abrahám, Attila Kardos
1Gottsegen György Országos Kardiológiai Intézet Budapest Haller u. 29. 1096. amihalcz@hotmail.com
Atrial fibrillation (AF) in chronic heart failure (CHF) patients can impact cardiac resynchronization therapy (CRT) effectiveness. This review explores AF
Area of Science:
- Cardiology
- Electrophysiology
- Heart Failure Management
Context:
- Atrial fibrillation (AF) and chronic heart failure (CHF) frequently coexist, posing significant clinical challenges.
- Cardiac resynchronization therapy (CRT) is a key device-based treatment for selected CHF patients, improving outcomes.
- Recent guidelines now include AF patients with heart failure as candidates for CRT.
Purpose:
- To review the prognostic significance of AF in heart failure.
- To examine the effects of CRT in patients with AF and heart failure.
- To discuss rhythm and rate control strategies for this patient population.
Summary:
- This review synthesizes current literature on AF in CHF, focusing on CRT.
- It addresses how AF can impede CRT efficacy and strategies to manage atrial tachyarrhythmias.
- The review covers prognostic relevance, CRT effects, and control strategies for AF in heart failure.
Impact:
- Provides insights into optimizing CRT for heart failure patients with atrial fibrillation.
- Highlights the importance of managing atrial tachyarrhythmias for improved CRT response.
- Informs clinical practice regarding guideline-based management of coexisting AF and CHF.
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