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Ultrasensitive diagnosis for an anthrax-protective antigen based on a polyvalent directed peptide polymer coupled to
Hye-Yeon Park1, Vinayakumar Gedi, Joungmok Kim
1Department of Chemistry, Hanyang University, Seoul, Korea.
Advanced Materials (Deerfield Beach, Fla.)
|October 15, 2011
Abstract:
A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDPP) exhibits increased binding affinity and detects anthrax protective antigen at low levels using a well-known zinc oxide nanorod detection system.
