Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cleaning, Sterilization, and Disinfection

Cleaning, Sterilization, and Disinfection

Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

Hand hygiene

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...

Standard Precaution

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...

Healthcare Associated Infections II: Preventive Measures

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

In Response to A Clinical Consensus Statement on Pulmonary Recurrent Respiratory Papillomatosis.

The Laryngoscope·2025

Same author

A Comprehensive Students-as-Teachers Program: Developing and Empowering Future Medical Educators.

Medical science educator·2024

Same author

Hospital outbreak of carbapenem-resistant Enterobacterales associated with a <i>bla</i><sub>OXA-48</sub> plasmid carried mostly by <i>Escherichia coli</i> ST399.

Microbial genomics·2022

Same author

Epidemiology and control measures of an OXA-48-producing Enterobacteriaceae hospital outbreak.

Infection prevention in practice·2021

Same author

Understanding why healthcare workers refuse the flu vaccine.

Journal of infection prevention·2020

Same author

Screening for antibiotic-resistant infection.

Nursing times·2015

Same journal

'The little things count': delivering dignified care.

Nursing times·2018

Same journal

The heart of the hospital.

Nursing times·2018

Same journal

The nurse's role in caring for people with dementia.

Nursing times·2018

Same journal

Hepatitis C and the ongoing challenge of genotype 3.

Nursing times·2018

Same journal

Implementing change in older people's acute care.

Nursing times·2018

Same journal

A total health economy approach to revalidation.

Nursing times·2018

See all related articles

Search research articles

Related Experiment Video

Updated: May 28, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

Tackling C difficile with environmental cleaning.

Yvonne Carter¹, Deborah Barry

¹The Royal Free Hampstead NHS Trust, London.

|October 18, 2011

Summary

This summary is machine-generated.

New sporicidal wipes significantly reduced C. difficile rates by 72% in an acute care setting. This highlights the effectiveness of peracetic acid wipes over traditional chlorine-based disinfectants for environmental cleaning.

More Related Videos

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Related Experiment Videos

Last Updated: May 28, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Area of Science:

Infection Control
Environmental Hygiene
Healthcare-Associated Infections

Background:

Traditional chlorine-based disinfectants pose risks due to high concentrations, causing irritation and corrosion.
These limitations make chlorine products unsuitable for near-patient environments, leading to compliance issues.
Peracetic acid and hydrogen peroxide-based products offer effective disinfection, even with heavy soiling.

Purpose of the Study:

To evaluate the impact of peracetic acid sporicidal wipes on Clostridioides difficile (C. difficile) infection rates.
To assess the efficacy of enhanced environmental cleaning in an acute care setting.

Main Methods:

An 18-month observational study (2006-2010) monitored C. difficile rates in inpatients aged two years and older.
A switch from chlorine-based to peracetic acid sporicidal wipes occurred in April 2008.
Patient bed days were tracked to control for variations in patient volume.

Main Results:

The mean C. difficile rate per 1000 patients decreased from six to two after introducing the wipes.
Rates fell below two per 1000 patients in early 2009.
A 72% overall reduction in C. difficile infection rates was observed.

Conclusions:

Implementing peracetic acid sporicidal wipes led to a substantial decrease in C. difficile rates.
Findings underscore the importance of revising environmental cleaning protocols to combat C. difficile.
Enhanced disinfection strategies are crucial for acute care settings.