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PD-L2 is predominantly expressed by Th2 cells

W Joost Lesterhuis, Henry Steer, Richard A Lake

    Molecular Immunology
    |October 18, 2011
    PubMed

    In response to a recently published article by Messal et al. (2011) in which the authors show that PD-L2 is expressed by activated T cells and ligation results in suppression of T cell proliferation and cytokine secretion, we here report that PD-L2 is differentially expressed by the diverse Th subsets, with predominant expression by Th2 cells.

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