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Updated: May 28, 2026

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
Published on: November 9, 2019
It takes two to Get3
Irmgard Sinning1, Gert Bange, Klemens Wild
1Heidelberg University Biochemistry Center, INF 328, 69120 Heidelberg, Germany. irmi.sinning@bzh.uni-heidelberg
Abstract:
Tail-anchored (TA) membrane proteins perform essential cellular functions. They are posttranslationally inserted into the endoplasmic reticulum (ER) membrane by interaction of the Get3 chaperone with the Get1/2 receptor. Two independent structural and functional analyses of the Get3/receptor complex by Stefer et al. and Mariappan et al. now provide insights into TA protein insertion.
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