Related Experiment Video

Updated: May 28, 2026

Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model
10:13

Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model

Published on: August 23, 2015

[Safety of cosmetics use for infants and children]

Ewa Kamińska1

  • 1Zakład Farmakologii, Instytut Matki i Dziecka, ul. Kasprzaka 17a, 01-211 Warszawa. ewa.kaminska@imid.med.pl

Medycyna Wieku Rozwojowego
|October 18, 2011
PubMed

Insights

Infant skin differs from adult skin in its reactivity to external factors. Understanding these differences is crucial for safe cosmetic use in children, preventing adverse effects from inappropriate ingredients.

Area of Science:

  • Dermatology
  • Pediatric Dermatology
  • Cosmetic Science

Context:

  • Infant skin exhibits unique anatomical and functional characteristics.
  • Young children's skin possesses distinct reactivity to exogenous substances compared to older individuals.
  • The developing skin barrier in neonates and infants presents specific vulnerabilities.

Purpose:

  • To highlight the distinct reactivity of infant skin to external factors.
  • To discuss the risks associated with inappropriate cosmetic ingredients and xenobiotics in pediatric skincare.
  • To provide a comprehensive review of ingredients commonly found in children's cosmetics.

Summary:

  • This paper examines the unique properties of newborn and infant skin, emphasizing its heightened sensitivity.
  • It details potential adverse effects stemming from the use of unsuitable cosmetic ingredients and xenobiotics in children.
  • A thorough overview of ingredients utilized in pediatric cosmetic products is presented, aiding in informed selection.

Impact:

  • Promotes safer cosmetic product development and selection for infants and children.
  • Enhances awareness among parents and healthcare providers regarding pediatric skincare risks.
  • Contributes to the scientific understanding of dermatological differences in pediatric populations.

More Related Videos

A Whole Mount In Situ Hybridization Method for the Gastropod Mollusc Lymnaea stagnalis07:33

A Whole Mount In Situ Hybridization Method for the Gastropod Mollusc Lymnaea stagnalis

Published on: March 15, 2016

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...