Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tandem Mass Spectrometry

Tandem Mass Spectrometry

Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...

Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule

Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule

In the AX proton spin system, proton A can sense the two spin states of a coupled proton X, resulting in a doublet NMR signal with two peaks of equal (1:1) intensity. When proton A is coupled to two equivalent protons (AX2 spin system), the spin states of each X can be aligned with or against the external field, creating three possible scenarios. This results in a 1:2:1 triplet signal, where the central peak corresponds to the chemical shift of A and is twice as large or intense as the others.

Mass Analyzers: Common Types

Mass Analyzers: Common Types

The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...

The Pauli Exclusion Principle

The Pauli Exclusion Principle

The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information:

Double Resonance Techniques: Overview

Double Resonance Techniques: Overview

Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...

Electron Paramagnetic Resonance (EPR) Spectroscopy: Organic Radicals

Electron Paramagnetic Resonance (EPR) Spectroscopy: Organic Radicals

Ideally, an unpaired electron shows a single peak in the EPR spectrum due to the transition between the two spin energy states. However, coupling interactions can occur between the spins of the unpaired electron and any neighboring spin-active nuclei. This hyperfine coupling results in hyperfine splitting, where the EPR signal is split into multiplets. The signals split into 2nI + 1 peaks, where n is the number of equivalent nuclei and I is the nuclear spin. These splitting patterns provide...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Basic evaluation of a novel 4D target and human body phantom.

Physics in medicine and biology·2019

Same author

Intravenous dexmedetomidine for cesarean delivery and its concentration in colostrum.

International journal of obstetric anesthesia·2017

Same author

A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip.

Nucleic acids research·2014

Same author

Dosage effects of the three Wx genes on amylose synthesis in wheat endosperm.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013

Same author

The expression and function of histamine H₃ receptors in pancreatic beta cells.

British journal of pharmacology·2013

Same author

[Liposome-encapsulated hemoglobin ameliorates brain dysfunction after transient cerebral ischemia in rats].

Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology·2012

Search research articles

Related Experiment Video

Updated: May 28, 2026

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps

Published on: August 17, 2017

Twin-electron biprism.

M Ikeda¹, A Sugawara, K Harada

¹Central Research Laboratory, Hitachi Ltd, Akanuma, Hatoyama, Hiki, Saitama 350-0395, Japan. masaki.ikeda.jf@hitachi.com

Journal of Electron Microscopy

|October 18, 2011

Summary

This summary is machine-generated.

A novel twin-electron biprism (TBP) doubles electron deflection angles without higher voltage. This advancement enhances electron holography by reducing unwanted Fresnel fringes, improving interference fringe clarity.

More Related Videos

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

Related Experiment Videos

Last Updated: May 28, 2026

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps

Published on: August 17, 2017

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

Area of Science:

Physics
Electron Optics
Interferometry

Background:

Conventional electron biprisms require high voltages for significant deflection.
Achieving large deflection angles is crucial for high-resolution electron interferometry.
Fresnel fringes can obscure data in electron holograms.

Purpose of the Study:

To develop a novel electron biprism for larger deflection angles at lower voltages.
To improve electron holography by minimizing Fresnel fringe intensity.
To optimize the setup for double-electron biprism interferometry.

Main Methods:

Design and fabrication of a twin-electron biprism (TBP) using two filament electrodes and ground plates.
Experimental measurement of interference-fringe spacing to determine deflection angles.
Analysis of TBP disposition in double-electron biprism interferometry.

Main Results:

The TBP achieved approximately twice the deflection angle compared to conventional electron biprisms.
The TBP operates effectively without increasing the applied voltage.
Optimal TBP positioning was identified to reduce Fresnel fringe intensity in electron holograms.

Conclusions:

The twin-electron biprism is a significant advancement for electron interferometry, offering enhanced deflection.
This technology improves electron holography by mitigating Fresnel fringe artifacts.
The TBP facilitates more precise electron optical experiments.