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Disseminated Mycobacterium chelonae subspecies chelonae infection with cutaneous and osseous manifestations
J J Drabick1, P E Duffy, C P Samlaska
1Infectious Disease Service, Walter Reed Army Medical Center, Washington, DC 20307-5000.
Abstract:
A 75-year-old man who had been receiving corticosteroids for treatment of chronic obstructive pulmonary disease presented with nodulopustular skin lesions, bone pain, and constitutional symptoms. Evaluation revealed a disseminated infection with Mycobacterium chelonae subspecies chelonae, with cutaneous and osseous involvement documented by histopathologic studies and cultures. The bone involvement is a novel observation for this subspecies. The patient was successfully treated with a three-drug regimen of tobramycin sulfate, erythromycin stearate, and ciprofloxacin hydrochloride. We present a discussion of the case in the context of the literature.