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Antenatal screening - the first and second trimester

Leonard Bonacquisto1

  • 1Maternal Serum Screening Laboratory, VCGS Pathology, Murdoch Childrens Research Institute, Royal Childrens Hospital, Parkville, Victoria. leonard.bonacquisto@ghsv.org.au

Australian Family Physician
|October 18, 2011
PubMed

Antenatal screening is performed in the first or second trimester to determine whether a pregnant woman's baby has an increased risk of having Down syndrome (a chromosomal abnormality affecting one in 500 pregnancies), Edward syndrome (one in 3000) or open neural tube defects (one in 750). First trimester screening combines results from a blood test with a nuchal translucency and nasal bone obstetric scan during the first trimester of pregnancy. Second trimester screening requires only a blood test. The screening approach varies across Australia; this article primarily describes the Victorian protocol.

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