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Fever and antipyresis in infection
Paul J Young1, Manoj K Saxena, Richard W Beasley
1Intensive Care Research Programme, Medical Research Institute of New Zealand, Wellington, New Zealand. paul.young@ccdhb.org.nz
Abstract:
Fever is an important mechanism of intrinsic resistance against infectious disease. A variety of studies point to a potential detrimental effect of temperature lowering in infectious disorders, but high-quality evidence from randomised controlled trials is lacking. In ambulatory care settings, we need to know whether antipyretics influence the severity and duration of illnesses and, in critically ill patients, whether antipyretics affect mortality.
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