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Using Scaffold Liposomes to Reconstitute Lipid-proximal Protein-protein Interactions In Vitro
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Probing the lipid-protein interface using model transmembrane peptides with a covalently linked acyl chain

Thomas K M Nyholm1, Bianca van Duyl, Dirk T S Rijkers

  • 1Biochemistry of Membranes, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands. tnyholm@abo.fi

Biophysical Journal
|October 19, 2011
PubMed
Summary

This study used deuterium-labeled lipids to probe protein-lipid interactions in membranes. Covalently linked lipid chains mimic non-covalently bound lipids, suggesting annular lipids have a general, not specific, role in transmembrane peptide interactions.

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