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Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
Selenacalix[3]triazines: synthesis and host-guest chemistry
Joice Thomas1, Wim Van Rossom, Kristof Van Hecke
1Molecular Design and Synthesis, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
Chemical Communications (Cambridge, England)
|October 19, 2011
Summary
Researchers expanded the heteracalixarene series with novel selenium-bridged macrocycles. These selenacalix[3]triazines exhibit unique supramolecular properties and can bind copper ions and anions.
Area of Science:
- Supramolecular Chemistry
- Macrocyclic Chemistry
- Organoselenium Chemistry
Background:
- Heteracalixarenes are macrocyclic compounds with diverse applications.
- Expanding this class with new heteroatoms like selenium is of significant interest.
- Understanding the synthesis and properties of novel macrocycles is crucial for materials science.
Purpose of the Study:
- To synthesize and characterize novel selenium-bridged cyclotrimeric macrocycles.
- To investigate the supramolecular features and coordination capabilities of these new compounds.
- To expand the known heteracalixarene family.
Main Methods:
- One-pot nucleophilic aromatic substitution reactions for synthesis.
- Characterization using standard spectroscopic techniques (e.g., NMR, Mass Spectrometry).
- Coordination studies with metal ions and anions.
Main Results:
- Successful synthesis of selenacalix[3]triazines.
- Demonstration of peculiar supramolecular features.
- The N-tridentate binding pocket effectively coordinated copper ions and various anions.
Conclusions:
- Selenacalix[3]triazines represent a new class of heteracalixarenes.
- These macrocycles possess unique supramolecular properties and coordination abilities.
- The findings open avenues for applications in host-guest chemistry and materials science.
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