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Updated: May 28, 2026

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
Published on: May 2, 2025
Pd2+···O3SR- interaction encourages anion encapsulation of a quadruply-stranded Pd complex to achieve chirality or
1Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo 153-8902, Japan.
Abstract:
Pd(2+)···O(3)SR(-) and CH···O(3)SR(-) interactions were found to play a crucial role in the encapsulation of organic sulfonates in a quadruply-stranded complex of Pd(2)L(4)-type. We have successfully employed this feature to achieve chirality induction by complexation with chiral guests as well as solubility increase by dendronization.
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