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Updated: May 28, 2026

An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
Published on: October 21, 2014
Omnis cellula e cellula revisited: cell biology as the foundation of pathology
Nicholas A Wright1, Richard Poulsom
1Centre for Digestive Diseases, Barts and the London School of Medicine and Dentistry, Turner Street, Whitechapel, London E1 2AD, UK. n.a.wright@qmul.ac.uk
Abstract:
This 2012 Annual Review Issue of The Journal of Pathology argues strongly that cell biology, in its many disciplines, underpins the foundation of our understanding of the mechanisms of disease-the holy grail of pathology. Our increasing knowledge of the human genome will not be enough to attain this goal without parallel developments in our comprehension of the results, at the cellular level, of these genetic changes. In the end, it is cell biology and cell biologists who will deliver this mission.
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