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Updated: May 28, 2026
08:31
Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
Published on: May 26, 2013
ViPR: an open bioinformatics database and analysis resource for virology research
Brett E Pickett1, Eva L Sadat, Yun Zhang
1Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Nucleic Acids Research
|October 19, 2011
Summary
The Virus Pathogen Database and Analysis Resource (ViPR) offers integrated data and tools for numerous virus families. This free resource aids researchers in developing diagnostics and therapeutics for priority viral pathogens.
Area of Science:
- Virology
- Bioinformatics
- Genomics
Background:
- The Virus Pathogen Database and Analysis Resource (ViPR) is a NIAID-funded initiative.
- ViPR serves as a centralized repository for data and analytical tools concerning multiple virus families.
Purpose of the Study:
- To provide a comprehensive, integrated platform for virology research.
- To support the development of diagnostics, prophylactics, and therapeutics for viral diseases.
Main Methods:
- ViPR aggregates diverse data types including sequence records, annotations, protein structures, and clinical metadata.
- It offers analytical tools for sequence analysis, alignment, phylogenetic construction, and variation determination.
- Users can combine data filtering and analysis workflows within personal 'Workbenches'.
Main Results:
- ViPR currently supports 14 human pathogenic virus families, with expansion planned.
- The resource includes sequence data, gene/protein annotations, 3D structures, and epitope locations.
- Integrated analytical tools facilitate comparative genomics and sequence variation studies.
Conclusions:
- ViPR provides a valuable, freely accessible resource for the global virology research community.
- The platform aims to accelerate the development of countermeasures against viral pathogens.
- Continued expansion and data integration will enhance its utility for future research endeavors.
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