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Updated: May 28, 2026

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
Published on: October 5, 2018
Influence of the sclerotomy use on mechanical incision competency in experimental model of vitrectomized eyes
Javier Benitez-Herreros1, Lorenzo Lopez-Guajardo, Cristina Camara-Gonzalez
1Department of Ophthalmology, University Hospital Principe de Asturias, Alcalá de Henares (Madrid), Spain.
Purpose:
To evaluate the influence of superior sclerotomy use (vitreous cutter or illumination probe entrance) on the postoperative sclerotomy closure competency using an experimental model of vitrectomized eye.
Methods:
Prospective, experimental, randomized and observer-masked experimental study in which 23 and 25-gauge transconjunctival sutureless vitrectomy was performed through oblique sclerotomies in the same cadaveric pig eye. Closure competency was determined by the resistance to intraocular fluid leak through the superior incisions in face of a progressive intraocular pressure (IOP) rise.
Results:
120 eyes included. In 52.5% of cases, the vitreous cutter probe sclerotomy showed intraocular fluid leakage first (p = 0.65). When comparing opening pressure values, there were no significant differences (p = 0.77) between the leakage pressure level of both sclerotomies depending on their use.
Conclusions:
Different uses of superior sutureless oblique sclerotomies do not seem to influence on TSV incision mechanical resistance to IOP rise in our experimental model.
