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Updated: May 28, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
[Hybrid cardiac SPECT-CT for coronary heart disease]
Piet L Jager1, Mohamed Mouden, Siert Knollema
1Isala klinieken, Zwolle, The Netherlands. p.l.jager@isala.nl
Abstract:
Cardiac SPECT-CT is a new hybrid technique that simultaneously produces non-invasive functional information (SPECT) and anatomical information about the coronary arteries (CT). Both types of information are crucial for optimal decision making regarding coronary revascularisation. The hybrid SPECT-CT scanner is very suitable for individual patient-tailored algorithms in which SPECT based ischaemia detection can be complemented with CT coronary angiography or vice-versa. In such approaches CT corrects the limitations of SPECT and SPECT corrects the limitations of CT. Initial studies report high diagnostic performance. The SPECT-CT technique is fast, comprehensive, efficient and even financially advantageous. SPECT-CT probably contributes to a more efficient use of invasive diagnostic coronary angiography.
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