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Updated: May 28, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Myocardial perfusion imaging by computed tomography: today and tomorrow

R P Marcus1, K Nikolaou, D Theisen

  • 1Department of Clinical Radiology, Ludwig-Maximilians University, Klinikum Grosshadern, Marchioninistrasse 15, Munich, Germany.

International Journal of Clinical Practice. Supplement
|October 20, 2011
PubMed

Insights

Cardiac CT imaging can now assess coronary artery disease (CAD) extent and function. This review covers new CT techniques for myocardial perfusion imaging, enhancing CAD assessment beyond traditional methods.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Technology

Background:

  • Coronary artery disease (CAD) assessment relies on imaging coronary artery stenosis and myocardial perfusion.
  • Established techniques like SPECT, PET, echocardiography, and MRI evaluate perfusion but not CAD morphology.
  • Cardiac CT excels at visualizing coronary atherosclerotic plaque and stenosis but lacks perfusion assessment.

Purpose of the Study:

  • To review recent advancements in cardiac CT for myocardial perfusion imaging.
  • To highlight the development of CT-based techniques for assessing both CAD morphology and function.

Main Methods:

  • Review of recent developments in cardiac CT.
  • Focus on CT-based myocardial perfusion imaging techniques.
  • Discussion of first-pass and dynamic CT acquisitions.

Main Results:

  • Cardiac CT is emerging as a reliable tool for visualizing coronary atherosclerotic plaque and stenosis.
  • Research is actively developing CT-based myocardial perfusion imaging techniques.
  • First-pass and dynamic CT acquisitions are key methods under investigation.

Conclusions:

  • Combining cardiac CT's morphological assessment with functional perfusion imaging holds great promise.
  • CT-based myocardial perfusion imaging aims to provide a comprehensive evaluation of CAD.
  • Further research in CT perfusion techniques is crucial for improved patient management.

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