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Related Experiment Videos

Transrectal sonography for serial evaluation of prostatic malignancy.

D D Dershaw1, H I Scher, T Smart

  • 1Department of Medical Imaging, Memorial Sloan-Kettering Cancer Center, New York, New York.

Urology
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

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Transrectal sonography accurately tracks prostate cancer regression and progression. However, prostate stability on serial imaging may not reflect clinical status in patients with prior radiation therapy.

Area of Science:

  • Urology
  • Oncology
  • Radiology

Background:

  • Prostate cancer management relies on monitoring disease status.
  • Transrectal sonography offers a non-invasive method for serial prostate imaging.
  • Evaluating the correlation between sonographic changes and clinical outcomes is crucial.

Purpose of the Study:

  • To correlate serial transrectal sonography findings of the prostatic bed with systemic disease changes in prostate cancer patients.
  • To assess the accuracy of sonography in identifying disease regression, progression, and stability.

Main Methods:

  • Serial transrectal sonograms were performed on 31 patients with prostate carcinoma.
  • Seventy-three sonograms were analyzed to evaluate interval changes in 42 instances.
  • Sonographic findings were correlated with clinical response and disease progression.

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Main Results:

  • Sonography correctly identified regression in 89% and progression in 91% of evaluated cases.
  • Sonographic assessment of stable disease was accurate in 56% of studies, but improved to 83% after excluding patients with prior radiation.
  • Prostate stability on sonography may be unreliable in patients with prior prostatic irradiation.
  • Sonographic nodules of varying echogenicity mirrored the treatment response of the total prostate volume.

Conclusions:

  • Transrectal sonography is a valuable tool for monitoring prostate cancer, particularly for detecting regression and progression.
  • Caution is advised when interpreting stable findings on serial sonography in patients with a history of prostatic irradiation.
  • Sonographic assessment of nodular changes correlates with overall treatment response.