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Updated: May 28, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Fluoroscopic findings of swallowing: comparison between preterm and full-term infants
Lenice de Fatima da Silva-Munhoz1, Karina Elena Bernadis Bühler
1Universidade de São Paulo, São Paulo, SP, Brasil.
Insights
Swallowing difficulties, including nasopharyngeal and gastroesophageal reflux, are common in preterm infants. Further research is needed to confirm if these swallowing alterations stem from functional immaturity.
Area of Science:
- Pediatric Gastroenterology
- Neonatology
- Swallowing Disorders
Background:
- Swallowing function is crucial for infant development.
- Preterm infants may exhibit unique feeding challenges compared to full-term infants.
- Fluoroscopic assessment provides insights into the mechanics of swallowing.
Purpose of the Study:
- To detail fluoroscopic swallowing findings in preterm infants (0-6 months).
- To correlate these findings with clinical signs, symptoms, and associated conditions.
- To compare swallowing dynamics in preterm versus full-term infants.
Main Methods:
- Retrospective analysis of fluoroscopic swallowing studies in infants aged 0-6 months.
- Inclusion of 40 infants: 23 preterm and 17 full-term.
- Review of associated medical records for clinical data.
Main Results:
- Nasopharyngeal and gastroesophageal reflux were prevalent in both preterm and full-term infants.
- No significant differences in the incidence of swallowing disorders were observed between groups.
- Preterm infants showed more cardiac issues and oxygen desaturation; full-term infants experienced more vomiting.
Conclusions:
- Nasopharyngeal and gastroesophageal reflux are key fluoroscopic findings in preterm infant swallowing.
- Further longitudinal studies are recommended to validate the hypothesis of swallowing immaturity as the cause.
Purpose:
To describe the fluoroscopic findings of swallowing in preterm infants with zero to six months of age, as well as the related diseases and clinical signs and symptoms, and to compare these findings with data obtained from full-term infants.
Methods:
The retrospective findings of fluoroscopic studies carried out in infants with zero to six months of age and their respective files were analyzed. Participants were 40 subjects divided into two groups: Preterm Group, composed by 23 preterm infants, and Full-Term Group, with 17 infants born full-term.
Results:
Nasopharyngeal and gastroesophageal reflux were the main fluoroscopic findings of swallowing in both groups. There was no difference between the groups regarding the presence of swallowing disorders. The Preterm Group presented more cardiac problems than the Full-Term Group. No differences were found between the groups regarding neurologic and respiratory problems. With respect to clinical signs and symptoms suggestive of swallowing disorders, the Preterm Group presented more oxygen desaturation and the Full-Term Group, more vomiting.
Conclusion:
Nasopharyngeal reflux and gastroesophageal reflux were the main fluoroscopic findings of swallowing in preterm infants with zero to six months of age. New follow-up studies with this population must be carried out to confirm the hypothesis that the swallowing alterations observed were due to immaturity in the swallowing function.
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