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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
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Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Related Experiment Video

Updated: May 28, 2026

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

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Published on: May 31, 2019

What does addiction mean to me.

Morten Hesse1

  • 1Aarhus University Centre for Alcohol and Drug Research Købmagergade 26E DK-1150 Copenhagen.

Mens Sana Monographs
|October 21, 2011
PubMed
Summary

Addiction, a compulsive need for substances, is a complex mental illness influenced by genetics and environment. Understanding addiction respectfully, like through motivational interviewing, is key to addressing substance use problems.

Area of Science:

  • Psychiatry and Behavioral Sciences
  • Neuroscience
  • Public Health

Background:

  • Addiction is defined as a compulsive need for and use of habit-forming substances.
  • It is recognized as a mental illness, historically classified under personality disorders but now considered a clinical syndrome.
  • Addiction leads to significant health, social, and economic challenges.

Purpose of the Study:

  • To explore the multifactorial nature of addiction, encompassing genetic and environmental influences.
  • To examine the clinical implications and conceptual evolution of addiction.
  • To discuss the impact of addiction on policy and therapeutic approaches.

Main Methods:

  • Review of diagnostic nomenclature and clinical understanding of addiction.
Keywords:
AddictionCauses and Consequences of AddictionDependence

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  • Analysis of etiological factors, including genetic predispositions and environmental interactions.
  • Examination of policy implications and therapeutic strategies, such as motivational interviewing.
  • Main Results:

    • Addiction is multifactorially determined, with significant genetic and environmental contributions.
    • The concept of addiction has evolved from personality disorders to a clinical syndrome.
    • Despite prohibitionist policies, substance use problems persist, highlighting the need for evolving approaches.

    Conclusions:

    • Addiction is a complex syndrome with biological and environmental underpinnings.
    • The conceptualization and societal perception of addiction significantly influence treatment and policy.
    • Respectful approaches, including motivational interviewing, offer promising avenues for addressing addiction and substance use disorders.