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[Effect of reducing injection on HFMD in children: a randomized controlled trial]
Yong-ping Mu1, Xiao-rong Chen, Ai-jun Zhang
1Shanghai Public Health Clinical Center, Shanghai 201508. ypmu8888@126.com
Summary
Reduning Injection (RI) offers faster fever reduction and body temperature recovery in children with hand, foot, and mouth disease (HFMD). This traditional Chinese medicine shows higher safety and aids in rash subsiding.
Area of Science:
- Pediatrics
- Infectious Diseases
- Traditional Chinese Medicine
Context:
- Hand, foot, and mouth disease (HFMD) is a common viral illness in children.
- Conventional treatments for HFMD include antiviral medications and antibiotics.
- Evaluating novel therapeutic approaches is crucial for improving patient outcomes.
Purpose:
- To assess the clinical efficacy and safety of Reduning Injection (RI) in treating pediatric HFMD.
- To compare RI's effects against Western medicine and a combination therapy.
Summary:
- A randomized controlled trial involved 76 children diagnosed with HFMD, assigned to Western medicine, RI, or combination therapy groups.
- RI and combination therapy significantly reduced fever onset time and body temperature recovery duration compared to Western medicine.
- No significant adverse drug reactions were reported, indicating a favorable safety profile for RI.
Impact:
- Reduning Injection demonstrates potential as an effective and safe treatment for pediatric HFMD.
- RI may offer advantages in symptom management, including faster fever resolution and rash improvement.
- This study supports the integration of RI into clinical practice for HFMD management.