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Updated: May 28, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

Iatrogenic immunosuppression and cutaneous malignancy

Jennifer L DePry1, Kurtis B Reed, Robert H Cook-Norris

  • 1Kansas City University of Medicine and Biosciences, 1750 Independence Ave, Kansas City, MO 64106, USA.

Clinics in Dermatology
|October 22, 2011
PubMed

Patients with autoimmune and inflammatory conditions often receive long-term immunosuppressive therapy. Some of the largest patient populations with iatrogenic immunosuppression include patients who have received solid-organ transplants or who have rheumatoid arthritis or psoriasis. Although treatments improve patient outcomes, individuals with immunosuppression subsequently may have an increased risk of skin cancer, including squamous cell carcinoma, basal cell carcinoma, and malignant melanoma.

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