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Published on: March 11, 2017
[Advance of polysorbate 80 for injection accessories]
1Experimental Research Center, China Academy of Chinese Medial Sciences, Beijing 100091, China. meiyu96@126.com
Summary
Polysorbate 80 is a common excipient in traditional Chinese medicine injections, often linked to adverse clinical reactions. This review details its properties and safety to guide rational use and promote TCM injection development.
Area of Science:
- Pharmacology
- Toxicology
- Chemistry
Context:
- Adverse clinical reactions are frequently associated with traditional Chinese medicine (TCM) injections.
- Polysorbate 80 is a common excipient in these formulations.
- Understanding excipient roles is crucial for TCM injection safety.
Purpose:
- To comprehensively review polysorbate 80, a key injection accessory.
- To summarize its chemical structure, properties, standards, pharmacology, safety, and toxicity.
- To provide a theoretical basis for the safe and effective use of TCM injections.
Summary:
- This review synthesizes literature and experimental data on polysorbate 80.
- Key aspects covered include chemical characteristics, quality standards, pharmacological activity, and safety evaluations.
- Toxicity studies are also included to provide a thorough overview.
Impact:
- To inform the rational selection of TCM formulations.
- To guide the safe and efficient application of injection accessories.
- To foster the healthy advancement of the TCM injection industry.
