Related Experiment Video
Updated: May 28, 2026

08:05
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
[Nodular presentation of a cryptogenic organizing pneumonia]
G Marques1, T Annweiler, D Raoux
1Faculté de médecine, université Jean-Monnet, 15 rue Ambroise-Paré, Saint-Étienne, France.
Revue De Pneumologie Clinique
|October 25, 2011
Summary
Cryptogenic organizing pneumonia can appear as a lung nodule on imaging, mimicking cancer. Definitive diagnosis requires histopathology due to critical differences in treatment and prognosis.
Area of Science:
- Pulmonology
- Radiology
- Pathology
Background:
- Cryptogenic organizing pneumonia (COP) is an inflammatory pulmonary disease.
- Characteristic radiologic findings include bilateral, migratory opacities.
Observation:
- A patient presented with chronic cough and an isolated peripheral lung nodule on chest X-ray.
- FDG-PET showed positive uptake, but bronchoscopy was inconclusive.
- Surgical resection revealed organizing pneumonia, with no identifiable cause.
Findings:
- COP can present as an isolated peripheral lung nodule.
- Positive PET uptake in COP can mimic malignancy.
- Histopathological examination is crucial for accurate diagnosis.
Implications:
- Early and accurate diagnosis of COP is vital.
- Distinguishing COP from lung cancer impacts patient prognosis and therapeutic strategies.
- Histopathology is essential for definitive COP diagnosis.
Related Concept Videos
Pneumonia II: Pathophysiology
The pathophysiology of pneumonia involves the following steps:
Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia I: Introduction
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations
Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...
COPD: Pathogenesis and Clinical Features
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...