Marginal structural models for estimating principal stratum direct effects under the monotonicity assumption

Yasutaka Chiba1

  • 1Division of Biostatistics, Clinical Research Center, Kinki University School of Medicine 377-2, Ohno-higashi, Osakasayama, Osaka 589-8511, Japan. chibay@med.kindai.ac.jp

Summary

This study introduces marginal structural models (MSMs) to estimate principal stratum direct effects (PSDEs), which represent causal effects within specific subgroups. These models offer a method for calculating direct treatment effects when mediators remain constant.

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