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Related Concept Videos

Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form the...
General Structure of a Vertebra01:30

General Structure of a Vertebra

A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous column.
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Overview of the Axial Skeleton01:09

Overview of the Axial Skeleton

The skeleton is subdivided into two major divisions—the axial skeleton and the appendicular skeleton. The axial skeleton forms the vertical, central axis of the body. It includes all of the bones of the head, neck, chest, and back. It protects the brain, spinal cord, heart, and lungs. It also serves as the attachment site for muscles that move the head, neck, and back and for muscles that act across the shoulder and hip joints to move their corresponding limbs.
The axial skeleton of the adult...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

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Related Experiment Video

Updated: May 28, 2026

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity
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Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

Published on: September 16, 2022

Adult spine deformity.

Christopher R Good1, Joshua D Auerbach, Patrick T O'Leary

  • 1Virginia Spine Institute, 1831 Wiehle Avenue, Reston, VA, 20190, USA, crgood@SpineMD.com.

Current Reviews in Musculoskeletal Medicine
|October 25, 2011
PubMed
Summary

Adult spinal deformity, affecting an aging population, presents with varied symptoms due to spinal degeneration. Treatment decisions for this condition depend on symptom severity and intervention risks.

Area of Science:

  • Orthopedics
  • Neurosurgery
  • Geriatrics

Background:

  • Adult spinal deformity (ASD) is a complex condition with diverse etiologies.
  • It is increasingly prevalent in the aging US population (adults 55-64 years).
  • Symptoms often involve progressive deformity, axial back pain, and neural element compression.

Purpose of the Study:

  • To summarize the presentation and management considerations for adult spinal deformity.
  • To highlight the growing impact of ASD on healthcare due to population aging.

Main Methods:

  • Review of clinical presentations and etiologies of adult spinal deformity.
  • Discussion of factors influencing treatment decisions (operative vs. nonoperative).

Main Results:

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  • ASD symptoms are linked to progressive, asymmetric spinal degeneration and potential neural compression.
  • Patient presentation varies, encompassing deformity progression, back pain, and neurological deficits.

Conclusions:

  • The increasing elderly population will likely lead to more cases of symptomatic spinal conditions.
  • Treatment strategies for ASD are individualized based on symptom severity, deformity type, and surgical risk.