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How to perform a critically appraised topic: part 1, ask, search, and apply
Aine Marie Kelly1, Paul Cronin
1Department of Radiology, Division of Cardiothoracic Radiology, University of Michigan Medical Center, University of Michigan Hospitals, Ann Arbor, 48109-5302, USA. ainekell@med.umich.edu
AJR. American Journal of Roentgenology
|October 25, 2011
Summary
This guide details the initial steps for critically appraised topics on diagnostic tests. It covers formulating questions, searching literature, and applying evidence levels for clinical practice.
Area of Science:
- Medical Research Methodology
- Evidence-Based Practice
- Diagnostic Test Evaluation
Background:
- Clinical decision-making requires rigorous evaluation of diagnostic test literature.
- A structured approach is essential for efficiently appraising research on diagnostic accuracy.
- Existing methods for critically appraising topics need clear, actionable steps.
Purpose of the Study:
- To outline the first three essential steps in performing a critically appraised topic (CAT) for diagnostic tests.
- To provide a framework for researchers and clinicians to systematically evaluate diagnostic test studies.
- To enhance the application of evidence-based medicine in clinical practice.
Main Methods:
- The article describes the 'Ask, Search, Apply' framework for CATs.
- Step 1: Formulate a clear clinical question regarding a diagnostic test.
- Step 2: Conduct a comprehensive literature search to identify relevant studies.
- Step 3: Apply a recognized level of evidence to the retrieved literature.
Main Results:
- The 'Ask' step ensures a focused and answerable clinical question.
- The 'Search' step emphasizes systematic and reproducible literature retrieval strategies.
- The 'Apply' step involves classifying the quality and strength of evidence for diagnostic test studies.
Conclusions:
- Critically appraised topics offer a structured methodology for clinical questions on diagnostic tests.
- This structured approach facilitates effective literature searching and evidence level assignment.
- Implementing CATs supports informed clinical practice and evidence-based recommendations.
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