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Related Experiment Video

Updated: May 28, 2026

Automatic Image Processing to Determine the Community Size Structure of Riverine Macroinvertebrates
08:56

Automatic Image Processing to Determine the Community Size Structure of Riverine Macroinvertebrates

Published on: January 13, 2023

Sample size tables for computer-aided detection studies.

Nancy A Obuchowski1, Stephen L Hillis

  • 1Department of Quantitative Health Sciences, Cleveland Clinic Foundation, OH 44195, USA. obuchon@ccf.org

AJR. American Journal of Roentgenology
|October 25, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Sample Size Calculation01:19

Sample Size Calculation

Knowledge of the sample size is the first requirement to conduct random sampling or an experiment. The sample size is the total number of units, observations, or groups (in some cases) used to get the data to estimate a population parameter. As the name suggests, the sample size is that of the sample drawn from the population and differs from the population size.
The sample size for the given experiment or sampling effort is fundamental to any study design. Sample size decides the number of...

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Calculating sample size for diagnostic accuracy studies with multiple findings is complex. This research offers tables and figures to aid in determining the necessary number of patients and readers for such studies, especially in computer-aided detection (CAD).

Area of Science:

  • Medical imaging analysis
  • Diagnostic accuracy research
  • Statistical methodology

Background:

  • Sample size calculation for multireader, multicase studies is complex.
  • Studies with multiple findings per case, common in computer-aided detection (CAD), present unique design challenges.

Purpose of the Study:

  • To modify existing sample size estimation methods for multireader, multicase studies with multiple findings.
  • To provide practical tools for researchers designing diagnostic accuracy studies.

Main Methods:

  • Adapted existing sample size estimation techniques to account for multiple findings per case.
  • Utilized data from two large CAD studies to estimate key parameters.

Main Results:

Related Experiment Videos

Last Updated: May 28, 2026

Automatic Image Processing to Determine the Community Size Structure of Riverine Macroinvertebrates
08:56

Automatic Image Processing to Determine the Community Size Structure of Riverine Macroinvertebrates

Published on: January 13, 2023

  • Presented sample size tables to estimate required patients and readers for studies with multiple findings.
  • Included figures to adjust reader numbers based on between-reader variability.

    • Conclusions:

    • The provided tables assist in assessing study feasibility with available resources.
    • Investigators should compute sample size using pilot data specific to their study design.