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Updated: May 28, 2026

Digestion of the Murine Liver for a Flow Cytometric Analysis of Lymphatic Endothelial Cells
Published on: January 7, 2019
An overview of lymphatic vessels and their emerging role in cardiovascular disease
1Interdepartmental Program in Vascular Biology and Therapeutics, CT, USA.
Abstract:
Over the past decade, molecular details of lymphatic vessels (lymphatics) have been rapidly acquired due to the identification of lymphatic endothelial-specific markers. Separate from the cardiovascular system, the lymphatic system is also an elaborate network of vessels that are important in normal physiology. Lymphatic vessels have the unique task to regulate fluid homeostasis, assist in immune surveillance, and transport dietary lipids. However, dysfunctional lymphatic vessels can cause pathology, while normal lymphatics can exacerbate pathology. This review summarizes the development and growth of lymphatic vessels in addition to highlighting their critical roles in physiology and pathology. Also, we discuss recent work that suggests a connection between lymphatic dysfunction and cardiovascular disease.
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