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Updated: May 28, 2026

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
Published on: June 17, 2025
Direct and indirect transmission of relationship functioning across generations
Miriam K Ehrensaft1, Heather M Knous-Westfall, Patricia Cohen
1Department of Psychology, John Jay College of Criminal Justice, and Division of Child and Adolescent Psychiatry, Columbia University at New York State Psychiatric Institute, New York, NY, USA. mehrensaft@jjay.cuny.edu
Abstract:
Relationship functioning is assumed to propagate across subsequent generations, but most studies have lacked appropriate methodologies to test this assumption prospectively. In a randomly selected sample of youth (N = 821) followed prospectively for over 25 years across multiple generations, we examined the association of romantic engagement (i.e., emotional involvement and closeness) between parents with offspring romantic relationship quality. We tested two developmental pathways linking parents' romantic engagement with offspring adult romantic relationship quality, the first operating via parenting practices, and the second operating via adolescent depression. Parents' romantic engagement predicted offspring romantic relationship quality a mean of 17 years later, net age and socioeconomic status. Results supported a developmental pathway from parents' romantic engagement at offspring mean age 14, to parenting at offspring mean age 16, to offspring socioemotional functioning at mean age 22, and offspring romantic relationship quality at mean age 33. However, the influence of parents' romantic engagement on offsprings' adult romantic relationship quality does not appear to operate via a pathway of adolescent depression. Implications for prevention are discussed.
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