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Updated: May 28, 2026

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders
Published on: February 3, 2021
Adenosine-induced coronary artery spasm: a case report
Montaser Ismail1, Nidal Asaad, Jassim Al-Suwaidi
1Department of Cardiology and Cardiac Surgery, Hamad Medical Corporation, Doha, Qatar.
Objective:
To describe an uncommon complication of intravenous adenosine administration.
Clinical Presentation And Intervention:
A 41-year-old female patient presented with palpitations due to supraventricular tachycardia. The patient was treated with intravenous adenosine with resolution of the tachycardia. Subsequently, the patient developed chest pain and ST segment elevation in the inferior leads that resolved with sublingual nitroglycerin.
Conclusion:
This report showed a case of coronary spasm secondary to the administration of adenosine. We therefore recommend that discretion be exercised when giving adenosine, especially to patients with an underlying tendency for vasospastic reactions.
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