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Related Concept Videos

Wheatstone Bridge01:29

Wheatstone Bridge

An ohmmeter is a resistance-measuring device. It works by applying a voltage to a resistor of unknown resistance and measuring the current across the resistor. The resistance value is deduced using Ohm's law. Usually, the standard configuration of an ohmmeter comprises a voltmeter or an ammeter. However, such configurations are limited in accuracy because the meters alter the voltage applied to the resistor and the current that flows through it.
Thus, for accurate resistance measurements, a...

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A Microfluidic Chip for ICPMS Sample Introduction
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Published on: March 5, 2015

Microfluidic Wheatstone bridge for rapid sample analysis.

Melikhan Tanyeri1, Mikhil Ranka, Natawan Sittipolkul

  • 1Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL 61801, USA.

Lab on a Chip
|October 28, 2011
PubMed
Summary
This summary is machine-generated.

Researchers created a microfluidic Wheatstone bridge for automated fluid sampling. This device precisely controls flow, enabling on-demand sample collection in microfluidic systems.

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Area of Science:

  • Microfluidics
  • Chemical Engineering
  • Biotechnology

Background:

  • Traditional methods for fluid sampling can be complex and time-consuming.
  • Precise control of fluid flow is essential in microfluidic devices for various applications.

Purpose of the Study:

  • To develop a microfluidic analogue of a Wheatstone bridge circuit.
  • To achieve automated, real-time fluid sampling in a flow-through device.
  • To demonstrate precise control over flow rate and direction within microchannels.

Main Methods:

  • Fabrication of a microfluidic device incorporating a Wheatstone bridge analogue.
  • Integration of an on-chip membrane valve acting as a variable resistor.
  • Implementation of an automated feedback control system to regulate valve opening and pressure drop.

Main Results:

  • Demonstrated precise control of fluid flow rate and direction in the microfluidic bridge.
  • Achieved complete stoppage of flow in the bridge channel by balancing resistances.
  • Enabled rapid, on-demand fluid sampling capabilities within the device.

Conclusions:

  • The microfluidic Wheatstone bridge offers a novel and adaptable approach for on-chip flow control.
  • This technology facilitates efficient sample manipulation and real-time analysis in microfluidic systems.
  • The device design provides key parameters for optimizing performance in microfluidic applications.