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Updated: May 28, 2026

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
Published on: April 17, 2020
Neurologic determination of death
Jeanne Teitelbaum1, Sam D Shemi
1Montreal Neurological Hospital, 3801 University Avenue, Room 364, Montreal, Quebec H3A2B4, Canada. jteitelbaum@hotmail.com
Abstract:
Death determined by neurologic criteria or brain death is better understood as brain arrest or the final clinical expression of complete and irreversible neurologic failure. Despite widespread national, international, and legal acceptance of the concept, substantial variation exists in the standards and their application, and there remains a need to clarify and standardize terminology (eg, ancillary and supplementary testing, brain death, or neurologic determination of death). The aim of this article is to review the specific criteria and requirements of brain death, paying special attention to areas of controversy and practice inconsistency.
