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Protamine-histone replacement and DNA replication in the male mouse pronucleus
Molecular Reproduction and Development
|January 1, 1990
Abstract:
The protamine to histone replacement in fertilized mouse eggs was studied by using antibodies to these proteins. Its course was followed with respect to DNA replication by autoradiography of 3H-thymidine-labeled fertilized eggs. It was found that protamines were replaced by histones before the onset of DNA replication.