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Leishmaniasis

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...

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Related Experiment Video

Updated: May 28, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

Leishmaniasis.

Elinor M Moore¹, Diana N Lockwood

¹Hospital for Tropical Diseases, University College London Hospital, London.

Clinical Medicine (London, England)

|November 1, 2011

Summary

This summary is machine-generated.

Leishmaniasis is a rare infectious disease in the UK. Consider leishmaniasis in patients with relevant travel history and consult specialists for diagnosis and treatment.

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Area of Science:

Infectious Diseases
Parasitology
Clinical Medicine

Background:

Leishmaniasis is an uncommon infectious disease globally.
It presents with diverse clinical manifestations.
The UK has a low incidence of leishmaniasis.

Observation:

Leishmaniasis diagnosis requires consideration of patient travel history.
The Mediterranean basin is a key endemic area.
Clinical presentations can be varied and non-specific.

Findings:

Specialised parasitology laboratories are essential for accurate diagnosis.
General physicians may lack familiarity with leishmaniasis.
Expert consultation is crucial for appropriate diagnostic and treatment strategies.

Implications:

Increased physician awareness of leishmaniasis is needed for early detection.
Referral to specialized centers improves patient outcomes.
Effective management relies on collaborative care between general practitioners and experts.