An electrochemical procedure to concentrate 99mTc availed from a zirconium [99Mo] molybdate gel generator

Successful use of electrochemical method to concentrate (99m)Tc obtained from a zirconium molybdate (Zr(99)Mo) gel generator is reported. The process consists of electrodeposition of the (99m)Tc in an oxalate bath on a small platinum electrode followed by recovery of (99m)Tc in a small volume of normal saline. The overall recovery of (99m)Tc was >90% with >99.99% radionuclidic purity and >99% radiochemical purity. The compatibility of the product in the preparation of (99m)Tc labeled formulations such as (99m)Tc-DMSA and (99m)Tc-EC was found to be satisfactory in terms of high labeling yields (>98%).