Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomized controlled trial.

European journal of endocrinology·2022
Same author

A Mycobacterial Systems Resource for the Research Community.

mBio·2021
Same author

Endovascular management of mycotic aortic aneurysms- A 20-year experience from a single UK centre.

Clinical radiology·2020
Same author

Estimating energy expenditure in vascular surgery patients: Are predictive equations accurate enough?

Clinical nutrition ESPEN·2017
Same author

OfftargetFinder: a web tool for species-specific RNAi design.

Bioinformatics (Oxford, England)·2015
Same author

A randomised controlled trial of two supervised exercise regimens and their impact on inflammatory burden in patients with intermittent claudication.

Vascular·2015
Same journal

Evaluation of generative artificial intelligence in producing anatomically distinct lipedema subtypes: A diagnostic accuracy study.

Phlebology·2026
Same journal

Obituary for professor Eberhard Rabe.

Phlebology·2026
Same journal

Endovenous vacuum-assisted laser ablation (VALA) for the treatment of great saphenous vein aneurysm close to the junction (Type I).

Phlebology·2026
Same journal

Response to the letter to the editor: "Methodological considerations in the evaluation of pain and central sensitization in lipedema".

Phlebology·2026
Same journal

Women's awareness and knowledge of lipedema in Turkey: Findings from a nationwide online survey.

Phlebology·2026
Same journal

Prevalence of saphenofemoral junction reflux and lower-limb venous diameters in kidney transplant recipients: A cross-sectional duplex ultrasound study.

Phlebology·2026
See all related articles

Related Experiment Video

Updated: May 28, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Is endovenous laser ablation possible while taking warfarin?

C L Delaney1, D A Russell, J Iannos

  • 1Department of Vascular Surgery, Repatriation General Hospital/Flinders Medical Centre, Adelaide, SA, Australia.

Phlebology
|November 1, 2011
PubMed
Summary
This summary is machine-generated.

Endovenous laser ablation (EVLA) effectively treats great saphenous vein (GSV) insufficiency in anticoagulated patients. This minimally invasive procedure offers a safe and successful option for managing venous ulcers in this challenging group.

More Related Videos

Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

Related Experiment Videos

Last Updated: May 28, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

Area of Science:

  • Vascular Surgery
  • Minimally Invasive Procedures
  • Phlebology

Background:

  • Patients with venous ulcers often require anticoagulation due to comorbidities, posing a therapeutic challenge.
  • Managing anticoagulation perioperatively for venous ulcer treatment can be complex, costly, and increase surgical risks.
  • Elderly patients with venous ulcers may exhibit poor adherence to compression therapy.

Purpose of the Study:

  • To evaluate the efficacy and safety of endovenous laser ablation (EVLA) for the great saphenous vein (GSV) in patients who remain on therapeutic anticoagulation.
  • To determine if EVLA can be a viable treatment option for the subgroup of patients with venous ulcers requiring anticoagulation.
  • To assess the outcomes of GSV EVLA in patients with CEAP classification 5 or 6 who continue therapeutic anticoagulation.

Main Methods:

  • Fifteen consecutive patients (CEAP 5 or 6) underwent standard great saphenous vein EVLA using a 1470-nm radial laser fiber.
  • Tumescent anesthesia was employed, and patients maintained therapeutic international normalized ratio (INR) levels throughout the procedure.
  • Clinical and duplex ultrasound follow-up was conducted at six weeks, and three, six, and 12 months post-treatment.

Main Results:

  • Successful occlusion of the great saphenous vein (GSV) was achieved in 14 out of 15 patients (93%).
  • One patient required a repeat successful treatment three months later.
  • No significant complications necessitating intervention were observed during the follow-up period.

Conclusions:

  • Endovenous laser ablation (EVLA) utilizing a 1470-nm radial fiber is an effective treatment for GSV insufficiency in therapeutically anticoagulated patients.
  • The procedure demonstrated minimal complications, making it a safe option for this patient cohort.
  • EVLA should be considered a valuable addition to the treatment options for anticoagulated patients with venous ulcers.