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OfftargetFinder: a web tool for species-specific RNAi design
R T Good1, T Varghese2, J F Golz3
1The Bio21 Institute School of Biosciences, The University of Melbourne, Melbourne 3010, Australia.
Motivation:
RNA interference (RNAi) technology is being developed as a weapon for pest insect control. To maximize the specificity that such an approach affords we have developed a bioinformatic web tool that searches the ever-growing arthropod transcriptome databases so that pest-specific RNAi sequences can be identified. This will help technology developers finesse the design of RNAi sequences and suggests which non-target species should be assessed in the risk assessment process.
Availability And Implementation:
http://rnai.specifly.org
Contact:
crobin@unimelb.edu.au.
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