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Updated: May 28, 2026

Multifocal Electroretinograms
Published on: December 4, 2011
ISCEV standard for clinical multifocal electroretinography (mfERG) (2011 edition)
Donald C Hood1, Michael Bach, Mitchell Brigell
1Departments of Psychology and Ophthalmology, Columbia University, New York, NY, USA. dch3@columbia.edu
The clinical multifocal electroretinogram (mfERG) provides local retinal function data by recording responses from the cone-driven retina. This updated ISCEV guideline specifies standards for mfERG testing and result reporting.
Area of Science:
- Ophthalmology
- Neuroscience
- Electrophysiology
Background:
- The clinical multifocal electroretinogram (mfERG) assesses local retinal function.
- Previous ISCEV guidelines for mfERG were published in 2007.
Purpose of the Study:
- To provide updated international standards for the clinical multifocal electroretinogram (mfERG) test.
- To specify guidelines for the performance and reporting of mfERG results.
Main Methods:
- Recording quasi-simultaneous local electroretinogram (ERG) responses.
- Utilizing a stimulus array of 61 or 103 hexagons.
- Testing under light-adapted conditions on the cone-driven retina.
Main Results:
- Established new standards for the basic clinical mfERG test.
- Defined procedures for reporting mfERG results.
Conclusions:
- The updated guidelines ensure consistent and reliable mfERG testing.
- These standards facilitate accurate assessment of local retinal function.
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