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Published on: November 28, 2018
An analysis of vascular surgery in elderly patients to determine whether age affects treatment strategy
Insights
Age does not significantly impact complication rates for endovascular arterial procedures, unlike open surgeries. Vascular surgeons should prioritize endovascular approaches for all patients, irrespective of age, for better outcomes.
Area of Science:
- Vascular Surgery
- Geriatric Medicine
- Interventional Cardiology
Background:
- Arterial disease incidence rises with age, increasing healthcare demands.
- Life expectancy improvements necessitate advanced vascular interventions.
- Evaluating age-related risks in vascular surgery is crucial for optimizing patient care.
Purpose of the Study:
- To compare intervention methods and complication rates in elderly (>75) versus younger vascular surgery patients.
- To determine if patient age influences management strategies for arterial disease.
- To analyze the impact of age on outcomes for open and endovascular procedures.
Main Methods:
- Prospective data collection of 6,144 arterial cases from 1978-2009.
- Comparative analysis of intervention methods and complication rates between age cohorts (<75 and >75).
- Statistical analysis using Fisher's exact test, relative risks, and 95% confidence intervals.
Main Results:
- Endovascular management is the primary approach for most arterial diseases.
- Age is a significant risk factor for death and myocardial infarction (MI) in open procedures (AAA repair, aorto-bifemoral reconstruction, lower limb bypass).
- Age did not significantly impact MI or death rates for endovascular procedures (EVAR, iliac/lower limb angioplasty).
Conclusions:
- A shift towards endovascular management for aortic, iliac, and femoral arterial disease is evident.
- Patient age significantly affects open procedure complications but not endovascular ones.
- Recommends endovascular approaches as first-line treatment for all patients, regardless of age.
Objectives:
The incidence of arterial disease increases with age. Increasing life expectancy in the western world will intensify demands on vascular surgeons with regard to increasing caseload, expanding patient selection criteria, and more complex and minimally-invasive treatment options. We analysed our arterial cases over the past 31 years (n = 6,144) and compared our methods of intervention and complication rates in the elderly population (>75) with the younger cohort, in order to determine whether age should influence our management strategies.
Methods:
Data were collected prospectively on all arterial cases from 1978 to 2009. Methods of intervention and corresponding complication rates in the over and under 75-year-old cohorts were analyzed utilizing Fisher's exact test to calculate two-sided p values, relative risks and 95% confidence intervals.
Results:
Endovascular management has evolved to become the first line approach for all arterial cases (except carotid disease). Age was a significant risk factor for death and MI for the open procedures of AAA repair (p = 0.049 and p = 0.007, respectively), aorto-bifemoral reconstruction (p < 0.0001 and p = 0.006) and lower limb bypass (p = 0.01 and p < 0.001). For endovascular procedures, age did not impact on MI rate for EVAR (p = 0.78) or death rates for EVAR (p = 0.46), iliac angioplasty (p = 0.62) or lower limb angioplasty (p = 0.29).
Conclusion:
A paradigm shift has occurred towards endovascular management of aortic, iliac and femoral arterial disease. Whilst patient age >75 significantly impacts on complication rates from index open vascular procedures, age does not impact upon complication rates of corresponding endovascular procedures. We, therefore, recommend an endovascular approach be adopted as first line for all patients, regardless of patient age.
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